Mycosis fungoides (MF) is a cutaneous malignant lymphoma with an extended clinical course. MF presents in series of dermatological manifestations, beginning with patches and plaques of the skin, and eventually evolving into tumours. Often MF can occur for extended periods without worsening of external symptoms, while the disease advances internally in organs such as lymph nodes, liver, spleen, lung, bone marrow, gastrointestinal tract, pancreas and kidney. The present report presents a clinical case in which gastrointestinal symptomatology occurred a decade after the first dermatolog­ical manifestation. Immunohistochemical analysis of the skin, along with small bowel biopsies revealed evidence of gastric T-cell lymphoma. To the best of our knowledge, the present study is the first todescribe such a case in the literature.

Mycosis fungoides and gastric t-cell lymphoma: a case report / Scali, E.; Presta, I.; Donato, A.; Schipani, G.; Dastoli, S.; Rossi, M.; Mignogna, C.; Malara, N.; Nistico, S. P.; Donato, G.. - In: MOLECULAR AND CLINICAL ONCOLOGY. - ISSN 2049-9450. - 13:3(2020). [10.3892/mco.2020.2085]

Mycosis fungoides and gastric t-cell lymphoma: a case report

Scali E.;Nistico S. P.;
2020

Abstract

Mycosis fungoides (MF) is a cutaneous malignant lymphoma with an extended clinical course. MF presents in series of dermatological manifestations, beginning with patches and plaques of the skin, and eventually evolving into tumours. Often MF can occur for extended periods without worsening of external symptoms, while the disease advances internally in organs such as lymph nodes, liver, spleen, lung, bone marrow, gastrointestinal tract, pancreas and kidney. The present report presents a clinical case in which gastrointestinal symptomatology occurred a decade after the first dermatolog­ical manifestation. Immunohistochemical analysis of the skin, along with small bowel biopsies revealed evidence of gastric T-cell lymphoma. To the best of our knowledge, the present study is the first todescribe such a case in the literature.
2020
cutaneous malignant lymphoma; duodenal T-cell lymphoma; mycosis fungoides; prognostic value; sezary syndrome; transformed mycosis fungoidesclinical challenges
01 Pubblicazione su rivista::01i Case report
Mycosis fungoides and gastric t-cell lymphoma: a case report / Scali, E.; Presta, I.; Donato, A.; Schipani, G.; Dastoli, S.; Rossi, M.; Mignogna, C.; Malara, N.; Nistico, S. P.; Donato, G.. - In: MOLECULAR AND CLINICAL ONCOLOGY. - ISSN 2049-9450. - 13:3(2020). [10.3892/mco.2020.2085]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1687146
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